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Sinclair Method Studies

Published on: 11/06/2025

This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.

How Long Does It Take for The Sinclair Method to Work?

How Long Does It Take for The Sinclair Method to Work?

How Long Does It Take for The Sinclair Method to Work?Bruce Rose
Published on: 25/09/2025

The Sinclair Method (TSM) is gaining traction as a science-backed way to change our relationship with alcohol. But a common and completely valid question we get is: how long does it take for The Sinclair Method to work?

The Sinclair Method (TSM)
The Science Behind The Sinclair Method

The Science Behind The Sinclair Method

The Science Behind The Sinclair MethodBruce Rose
Published on: 24/09/2025

Alcohol has long been used to numb, to celebrate, and to escape—the story quickly turns from one of choice to compulsion. Traditional recovery methods often push for immediate abstinence, yet many find this approach unsustainable.

The Sinclair Method (TSM)
Claudia Christian: Advocate for the Sinclair Method

Claudia Christian: Advocate for the Sinclair Method

Claudia Christian: Advocate for the Sinclair MethodBruce Rose
Published on: 23/09/2025

Claudia Christian, best known for her acting roles in Babylon 5 and 9‑1‑1, is also the founder and CEO of the C Three Foundation. She is a passionate proponent of The Sinclair Method as a science-based medication-assisted approach to alcohol use disorder

The Sinclair Method (TSM)
Do I Need a Detox to Start The Sinclair Method?

Do I Need a Detox to Start The Sinclair Method?

Do I Need a Detox to Start The Sinclair Method?Bruce Rose
Published on: 22/09/2025

For many, the word “detox” brings up images of cold-turkey abstinence, withdrawal symptoms, and white-knuckled willpower. But what if we told you that there’s a method that flips this idea on its head?

The Sinclair Method (TSM)
Is Naltrexone and The Sinclair Method Available in Ireland?

Is Naltrexone and The Sinclair Method Available in Ireland?

Is Naltrexone and The Sinclair Method Available in Ireland?Bruce Rose
Published on: 19/09/2025

Naltrexone is a prescription-only medication approved to help treat alcohol dependence in Ireland. It works by blocking the brain’s opioid receptors, reducing the sense of pleasure from alcohol. This dampens the reward cycle and gradually lessens alcohol cravings.

The Sinclair Method (TSM)
The Role of Endorphins in Alcohol Dependency: What You Need to Know

The Role of Endorphins in Alcohol Dependency: What You Need to Know

The Role of Endorphins in Alcohol Dependency: What You Need to KnowBruce Rose
Published on: 18/09/2025

Endorphins are naturally occurring chemicals in the brain that help us manage pain and boost pleasure. Often called the body’s “natural opioids”, they are released during activities like exercise, laughing, eating, and social bonding. When endorphins flood the brain, we feel good — relaxed, happy, or even euphoric.

The Sinclair Method (TSM)
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